Evidence and medicines

Uncertainty in Pharmacology: Epistemology, Methods and Decisions

This volume covers a wide range of topics concerning methodological, epistemological, and regulatory-ethical issues around pharmacology. The book focuses in particular on the diverse sources of uncertainty, the different kinds of uncertainty that …

Randomized trials are not black boxes

Randomized trials are frequently treated as if they are a black box, but they are not.

Evidence and Medicines

Research related to evidence and medicines.

The use of mechanistic evidence in drug approval

This paper highlights the many ways that mechanistic evidence supports drug approval.

The randomized controlled trial: internal and external validity

A challenge for Evidence-Based Policy

Why randomised interventional studies

What does randomisation acheive?

Evidence Based Medicine Must Be...