Adam La Caze
Evidence and medicines
Uncertainty in Pharmacology: Epistemology, Methods and Decisions
This volume covers a wide range of topics concerning methodological, epistemological, and regulatory-ethical issues around pharmacology. The book focuses in particular on the diverse sources of uncertainty, the different kinds of uncertainty that …
Randomized trials are not black boxes
Randomized trials are frequently treated as if they are a black box, but they are not.
Evidence and Medicines
Research related to evidence and medicines.
The use of mechanistic evidence in drug approval
This paper highlights the many ways that mechanistic evidence supports drug approval.
The randomized controlled trial: internal and external validity
A challenge for Evidence-Based Policy
Why randomised interventional studies
What does randomisation acheive?
Evidence Based Medicine Must Be...